“NMR and Chemistry” by J.W. & Brian E. is a comprehensive textbook that explains the principles and applications of nuclear magnetic resonance (NMR) spectroscopy in chemistry. The book is organized into 10 chapters, covering a wide range of topics from the basics of NMR to more advanced techniques and applications.
Chapter 1: Introduction
The book begins with an introduction to NMR, including the historical development of the technique and the basic principles of NMR spectroscopy. The authors explain the relationship between magnetic fields and nuclear spin, as well as the factors that affect NMR spectra.
Chapter 2: Chemical Shift
Chapter 2 focuses on chemical shift, which is one of the most important concepts in NMR spectroscopy. The authors explain the origin of chemical shift, the factors that influence it, and how it can be used to identify and quantify compounds.
Chapter 3: Spin-Spin Coupling
In Chapter 3, the authors discuss spin-spin coupling, which arises from the interaction between nuclear spins. They explain how spin-spin coupling leads to splitting of NMR signals and how it can be used to obtain structural information about molecules.
Chapter 4: Relaxation
Chapter 4 covers relaxation, which refers to the process by which the excited nuclear spin returns to its ground state. The authors explain the different types of relaxation, including T1 and T2 relaxation, and how they can be measure and used to obtain information about molecular dynamics.
Chapter 5: Advanced Techniques
Chapter 5 introduces some of the more advanced techniques in NMR spectroscopy, including two-dimensional NMR, solid-state NMR, and NMR imaging. The authors explain the principles behind these techniques and how they can be use to obtain more detailed information about molecular structure and dynamics.
Chapter 6: Applications in Organic Chemistry
Chapter 6 focuses on the applications of NMR spectroscopy in organic chemistry. The authors provide examples of how NMR can be use to identify and characterize organic compounds, as well as how it can be use in synthetic chemistry to monitor reactions and determine reaction mechanisms.
Chapter 7: Applications in Inorganic Chemistry
In Chapter 7, the authors discuss the applications of NMR spectroscopy in inorganic chemistry. They provide examples of how NMR can be use to study metal complexes and coordination compounds, as well as how it can be use to study the structure and properties of materials.
Chapter 8: Applications in Biochemistry
Chapter 8 covers the applications of NMR spectroscopy in biochemistry. The authors explain how NMR can be use to study the structure and dynamics of proteins and nucleic acids, as well as how it can be use in drug discovery and development.
Chapter 9: Applications in Environmental Chemistry
Chapter 9 focuses on the applications of NMR spectroscopy in environmental chemistry. The authors explain how NMR can be use to study the structure and properties of natural products. As well as how it can be use in environmental monitoring and remediation.
Chapter 10: Future Developments
In the final chapter, the authors discuss some of the future developments in NMR spectroscopy. Including advances in hardware and software. As well as new applications of the technique in areas such as materials science and nanotechnology.
Conclusion
Overall, “NMR and Chemistry” is an excellent textbook. That provides a comprehensive introduction to the principles and applications of NMR spectroscopy in chemistry. The book is well-written and accessible to readers with a basic understanding of chemistry. It includes many helpful examples and illustrations. The authors also provide a wealth of references for readers who want to explore the topic in more depth. I would highly recommend this book to anyone who is interest in learning about NMR spectroscopy.